NVIDIA has released version 4.1 of its CUDA Toolkit for general purpose GPU computing.
There is a lot in this release, including a compiler based on LLVM, which will make it easier to support other programming languages; 1000 new imaging functions; and a re-designed visual profiler.
There is also an update to Parallel Nsight, for debugging and profiling CUDA applications in Visual Studio. This is free, though you have to register as an NVIDIA developer. You need this update to work with the 4.1 toolkit.
You do have to update your graphics card driver:
using a new build which NVIDIA has not gotten around to signing:
Still, lots of goodies here and a must-have for developers wishing to put their NVIDIA GPU to work for more than just games.