I currently travel with a Windows 8 slate, the slate being the retail Samsung Series 7 model (similar but not the same as the one given to Build attendees in 2011).
It is a decent machine with good performance, but has one considerable annoyance. From time to time, when waking the device from sleep or even turning on from cold, the screen stops responding to touch. The crude fix is to reset it by turning it off, then holding down the power button so it reboots. Open documents may be lost of course.
I do not have a cure for this behaviour, though I would love to know. However I have discovered the cause, which is that one or both Intel USB host controllers fails to start. You can see the problem in Device Manager:
How do you even get to this screen? Well, on my machine, if the top Intel host controller has a problem, then pen input fails but touch works. If the second Intel host controller fails, touch input fails but pen input works. If both fail (which also happens) you are sunk unless you can remote desktop in from another machine on the network.
Once you are in – via pen, touch, or remote desktop – right-click the offending controller and choose Disable. Then right-click again and choose Enable. This will fix the problem until next time.
A likely fix would be an updated driver for the host controller. The current driver dates from 2006.
However I cannot easily find anything more up to date.
Update: I have succeeded in updating the driver to one from February 2013 but it does not fix the problem. My conclusion is that the error in the USB Enhanced Host Controller is the symptom and not the cause of the issue. It is a resume or power-on problem; such as something happening too quickly or in the wrong order. Again, suggestions welcome!